Regular Article THROMBOSIS AND HEMOSTASIS Interaction of factor XIII subunits
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چکیده
assay–typebinding assay, the equilibriumdissociation constant (Kd) for the interactionwas established in the range of 10 M. Based on the measured Kd, it was calculated that in plasma approximately 1% of FXIII-A2 should be in free form. This value was confirmed experimentally by measuring FXIII-A2 in plasma samples immunodepleted of FXIII-A2B2. Free plasma FXIII-A2 is functionally active, and when activated by thrombin and Ca, it
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تاریخ انتشار 2014